We are often advertising research studentship and post doc positions (please see FindAPhD and jobs.ac.uk). Do get in touch if you would like to discuss these or any other research opportunities in our lab.
Selected Publications
Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis, Jones, S. A., Ruprecht, J. J., Crichton, P. G. & Kunji, E. R. S. 2024, Trends in Biochemical Sciences. 49, 6, p. 506-519 14 p.
Two-stage evolution of mammalian adipose tissue thermogenesis, Keipert, S., Gaudry, M. J., Kutschke, M., Keuper, M., Dela Rosa, M. A. S., Cheng, Y., Monroy Kuhn, J. M., Laterveer, R., Cotrim, C. A., Giere, P., Perocchi, F., Feederle, R., Crichton, P. G., Lutter, D. & Jastroch, M. 2024, Science. 384, 6700, p. 1111-1117 7 p.
Structural basis of purine nucleotide inhibition of human uncoupling protein 1, Jones, S. A., Gogoi, P., Ruprecht, J. J., King, M. S., Lee, Y., Zögg, T., Pardon, E., Chand, D., Steimle, S., Copeman, D. M., Cotrim, C. A., Steyaert, J., Crichton, P. G., Moiseenkova-Bell, V. & Kunji, E. R. S. 2023, Science Advances. 9, 22, eadh4251.
Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis, Cavalieri, R., Hazebroek, M. K., Cotrim, C. A., Lee, Y., Kunji, E. R. S., Jastroch, M., Keipert, S. & Crichton, P. G. 2022, Molecular Metabolism. 62, 101526.
The molecular mechanism of transport by the mitochondrial ADP/ATP carrier (2019) Ruprecht, J. J., King, M. S., Zögg, T., Aleksandrova, A. A., Pardon, E., Crichton, P. G., Steyaert, J. & Kunji, E. R. S. 2019, Cell. 176, 3, p. 435-447.e15 13 p.